I myself build software in this space and generally its productivity-ish-tools.
Here's a list of 70 macOS apps that received updates _today_ https://macupdater.com/app_updates/index-2025-01-27.html
That's because you are mostly interested in those things.
> Is anyone working on a software product that (a) targets a non-mobile, non-server device and (b) is for sale, as opposed to Open-source?
None of that is "opposed to Open-source". Anyway, if you use Windows or macOS, then open your platform's "app store" and take a look at literally any category but "free (as in beer)".
Yes. There is a whole world outside of your bubble.
Music production/ synthesis
Graphics / 3D / animation
Plus untold business cases