Most memorable JavaScript projects/moments in your history?

Just a couple of hours ago, a submission to HN was "Significant JavaScript projects from 2006 to 2020" (https://news.ycombinator.com/item?id=24142462) which at least for me, leaves out a lot of projects that was part of my early JavaScript career, such as Prototype.js, Backbone, Angular (v1) and others.

Since obviously this list leaves a lot out of the history of JavaScript and related technologies, what sticks out the most for you? Could be libraries, ways of developing software, compile-to-JS languages (CoffeeScript comes to mind) or any other fond (or non-fond) memories related to JavaScript and maybe even the web in general.

I'm not the oldest web developer around, I'm sure, but I'd love to hear more about what people feel this list is missing, because it's a lot.