Provided that most of you use their hand to write in front of a computer, that would be a very interesting problem in case somebody for any reason lose the ability to use some fingers.
Not to mention that it would be a problem regardless, but especially for those who are paid for typing in a keyboard
All fingers and thumbs gone - that would suck. Hopefully the bionic options improve and come down in price. Otherwise, automation and voice commands would be a big help for most things.
Frankly, interacting with the computer would be worse than if you had your fingers but I would rank that very low on the list. Computers have more accessibility tools than most physical objects. Imagine trying to open jar lids, using can openers, undoing twist ties - and these are common barriers to eating many foods just to survive by yourself.